![FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution](https://blog.addgene.org/hubfs/10_19-12_19/FLExOptogenetics_AA_2019_10_10/FLEx-switch.png)
FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution
![Genes | Free Full-Text | Administration of AAV-Alpha Synuclein NAC Antibody Improves Locomotor Behavior in Rats Overexpressing Alpha Synuclein | HTML Genes | Free Full-Text | Administration of AAV-Alpha Synuclein NAC Antibody Improves Locomotor Behavior in Rats Overexpressing Alpha Synuclein | HTML](https://www.mdpi.com/genes/genes-12-00948/article_deploy/html/images/genes-12-00948-g001.png)
Genes | Free Full-Text | Administration of AAV-Alpha Synuclein NAC Antibody Improves Locomotor Behavior in Rats Overexpressing Alpha Synuclein | HTML
![Cre-loxp system and Viral vector (AAV and adenovirus)-based Cre tools (AAV-Cre and Ad-Cre) | GeneMedi Cre-loxp system and Viral vector (AAV and adenovirus)-based Cre tools (AAV-Cre and Ad-Cre) | GeneMedi](https://www.genemedi.net/images/CRE06.webp)
Cre-loxp system and Viral vector (AAV and adenovirus)-based Cre tools (AAV-Cre and Ad-Cre) | GeneMedi
📽️This video clip is from our youtube video, "Conditional gene expression using the Cre Lox FLEx vector switch!". In the full video, we review the basics of the Cre Lox system and
![A rapid in vitro method to flip back the double-floxed inverted open reading frame in a plasmid | BMC Biotechnology | Full Text A rapid in vitro method to flip back the double-floxed inverted open reading frame in a plasmid | BMC Biotechnology | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12896-018-0462-x/MediaObjects/12896_2018_462_Fig1_HTML.png)
A rapid in vitro method to flip back the double-floxed inverted open reading frame in a plasmid | BMC Biotechnology | Full Text
![FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution](https://blog.addgene.org/hs-fs/hubfs/10_19-12_19/FLExOptogenetics_AA_2019_10_10/FLEx-switch-strategy.jpg?width=600&name=FLEx-switch-strategy.jpg)
FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution
![Frontiers | Novel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons Frontiers | Novel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons](https://www.frontiersin.org/files/Articles/31179/fncir-06-00047-r4/image_m/fncir-06-00047-g005.jpg)
Frontiers | Novel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons
![A photoactivatable Cre–loxP recombination system for optogenetic genome engineering | Nature Chemical Biology A photoactivatable Cre–loxP recombination system for optogenetic genome engineering | Nature Chemical Biology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fnchembio.2205/MediaObjects/41589_2016_Article_BFnchembio2205_Fig1_HTML.jpg)
A photoactivatable Cre–loxP recombination system for optogenetic genome engineering | Nature Chemical Biology
![Highly selective transgene expression through double-floxed inverted orientation system by using a unilateral spacer sequence | bioRxiv Highly selective transgene expression through double-floxed inverted orientation system by using a unilateral spacer sequence | bioRxiv](https://www.biorxiv.org/content/biorxiv/early/2022/04/12/2022.04.11.487972/F2.large.jpg)